Evaluation of wound healing activity of topical phenytoin in an excision wound model in rats

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Evaluation of Wound Healing Effect of Topical Phenytoin on Excisional Wound in Albino Rats

OBJECTIVES Wound healing is a significant healthcare problem in today's medical practice. Despite extensive treatment modalities that are supposed to hasten the wound healing process, the outcomes of existing methods are far from optimal. One such agent that has been tried previously and found controversial in wound healing is phenytoin. In this study, the wound-healing efficacy of phenytoin wa...

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Wound healing activity of the flowers of Lilium candidum L. in burn wound model in rats

Background: Ethnomedicinal plants are of interest for treatment of various wound types. Objective: This study aimed to evaluate burn wound healing potential of the hydro-alcoholic extract of the flowers of Lilium candidum L. in rats. Methods: DPPH free radical scavenging power, total flavonoids, and the phenolic content of the extract were evaluated. Following burn wound induction, 30 Wistar ra...

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Effect of topical phenytoin on burn wound healing in rats.

To evaluate the effect of phenytoin on burn wounds and to compare the effect of the combination of topical phenytoin preparation in dexamethasone treated burn wounds in rats, partial thickness thermal burn wounds were inflicted upon five groups of six rats each. Group I was assigned as control, Group II received the standard silver sulphadiazine, Group III was given topical phenytoin and Group ...

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Evaluation of the Wound Healing Activity of a Traditional Compound Herbal Product Using Rat Excision Wound Model

Iranian Traditional Medicine (ITM) manuscripts contain prescriptions that have long been used for healing of wounds. The present study evaluates the healing effect of a poly herbal paste (PHP), retrieved from ITM sources, containing Aloe vera, Commiphora myrrha and Boswellia carteri using rat excision wound model. Excision wounds were induced in six groups consisting of six rats each. Group 1 r...

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ژورنال

عنوان ژورنال: International Journal of Basic & Clinical Pharmacology

سال: 2015

ISSN: 2319-2003

DOI: 10.5455/2319-2003.ijbcp20150225